by researchers from KTH Royal Institute of Technology in Stockholm, the technique brings together the structural and mechanical performance of inexpensive cellulose nanofibrils with the medicinal properties of spider silk, which is difficult and expensive to fabricate on a larger scale.
The bioactive properties of spider silk have been known for centuries. In ancient Rome, spider webs were used to dress soldiers’ battle wounds. But producing large scale amounts of spider silk material today has proven an expensive process, which often relies on fossil-based sources.
KTHresearcher says that by comparison, wood-based nanocellulose is cheap and sustainable. Furthermore, the technique of combining it with only small amounts of spider silk protein yields a biofunctional material that can be used for such medical purposes as promoting cell growth.
“The strength of the fiber is significantly better than any man-made, silk-based material to our knowledge, and on the same level as what can be found in nature from spiders,” says , a researcher with the .
Today, cellulose nanofibrils obtained from trees receive scientific and commercial attention not only because they are renewable, biodegradeable, virtually non-toxic and available in large volumes, but they also offer outstanding mechanical properties.
Söderberg says that the fabricated filament material could potentially be used, for example, as a building-block for ligaments.
To make the material, the researchers use what are known as recombinant silk proteins. Rather than using a spider as host, the researchers take the gene encoding the silk protein and combine it with a gene encoding some desired function, such as cell-binding, Hedhammar says. “We transfer this fusion gene to a simple, easily-cultured lab bacteria, which then produces the functionalized silk proteins that can be purified in the lab,” she says.
Söderberg says technique uses hydrodynamics to align the fibers’ internal structure on the micro- and nano-scale. “When the nanocellulose is aligned in the macroscopic material we can achieve super performance,” he says.
Source : KTH Royal Institute of Technology